Using the laser-induced spectroscopy method to analyze electrolytes in blood serum

The analysis of electrolytes in the blood serum helpsto identify the pathological state of the human body by means of indicators of calcium, sodium and potassium. It is possible to quantify the indicated indicators by means of spectroscopy (LIBS), which makes it possible to identify sufficiently accurate data in numerical values. The aim of the study is to form the possibility of a more accurate prediction of probable diseases by means of indicators of sodium, calcium and potassium in the blood. The research process was carried out by using the available biomaterials presented by the INVITRO laboratory of Makhachkala, the Republic of Dagestan, which were subsequently used for the analysis of electrolytes in blood serum on filter paper and slides. In order to predict the concentrations of potassium, sodium and calcium under consideration by means of LIBS, the method of partial least squares regression was applied. For serum samples, higher prediction accuracy with excellent linearity was achieved both on slides and on filter paper. For blood serum on slides, the prediction accuracy of K, Na, Ca was 1,45 %, 0,61 % and 3,80 %. Moreover, for blood serum on filter paper with the existing errors were 7,47 %, 1,56 % and 0,52 %. Results. The results of the study suggest that LIBS portable tools will be an excellent tool for clinical practice in real time.

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