The study of the informative characterization of the contours of focal formations of the pancreas for the purpose of differential diagnosis of chronic pancreatitis and ductal adenocarcinoma.

Differential diagnosis of focal pancreatic pathology is a complex clinical task. The method of endoscopic ultrasonography is the most informative in the detailed visualization of the pancreatic parenchyma and is used as a clarifying method in the diagnosis of focal pathology of the organ, which is provided by high-resolution images due to the minimal distance of the sensor from the object under study. One of the informative criteria for the differential diagnosis of the pathology under study is the characteristic of the contours of focal formations. The aim of the work was to improve the quality of differential diagnosis of focal pancreatic pathology according to endoscopic ultrasonography based on the analysis of the characteristics of the contours of focal formations with an assessment of their informative value. The results of endoscopic ultrasonography of 109 patients with solid tumors of the pancreas and 40 patients with chronic pancreatitis were analyzed. The endoscopic video system of the Olympus EVIS EXERA II company with the EU-ME1 ultrasound processor was used. Using the developed universal algorithms, the most homogeneous fragments of the region of interest are selected from the primary video materials, on the basis of which a scale of characteristics of the contours of the considered focal pathology is formed. Eight main types of contours corresponding to chronic focal pancreatitis and ductal adenocarcinoma with various degrees of differentiation were identified. The obtained data allowed us to construct a histogram with subsequent statistical analysis of the results, which showed the prospects of the proposed method of differential diagnosis of pancreatitis and oncological diseases and the synthesis decision rules.

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