ONE-WAY ANALYSIS OF VARIANCE OF SOME FACTORS INFLUENCE ONTHE SLEEP QUALITY IN COPD AND UNDER MELATONIN ACTION

Оne-way analysis of variance revealed the negative impact of gender, age, duration of disease, nicotine addiction, the number of hospitalizations and the number of exacerbations with an appeal to the person skilled in the year, the level of anxiety and depression, TSHH the quality of sleep in patients with moderate development of chronic obstructive pulmonary disease (COPD). Acceptance of melatonin (the scheme) patients with moderate COPD leads to statistically zanchimomu improving sleep quality, reduce the number of exacerbations with the call of a general practitioner, emergency medical care and hospitalization in the background to improve the psycho-emotional sostoyaniya. Odnako this regimen of melatonin in patients with severe COPD does not lead to effective correction of sleep disorders

1. Agusti A.G. Systemic effects of chronic obstructive pulmonary disease / A.G. Agusti // Proc. Am. Thorac. Soc. 2005. Vol. 2. P. 367-370.

2. Celli B.R., MacNee W. Standards for the diagnosis and treatment of patients with COPD: a summary of the ATS / ERS position paper / B.R. Celli, W. MacNee // Eur. Respir. J. 2004. Vol. 23, No. 6. P. 932-946.

3. Tsvetikova L.N. Antistreptolizin i pokazateli oksidativnogo stressa pri KhOBL s soputstvuyushchey ishemicheskoy bolezn'yu serdtsa / Tsvetikova L.N., Yu.N. Chernykh, N.V. Lobeeva // Vestnik Voronezhskogo instituta vysokikh tekhnologiy. 2015. No. 15. S. 15-17.

4. Buzunov R.V. Tsirkadiannye rasstroystva sna u zhiteley megapolisa / R.V. Buzunov, E.V Tsareva // Terapevticheskiy arkhiv. 2013. T. 85, № 10. S. 79-82.

5. Budnevskiy A.V. Metody diagnostiki i profilaktiki patsientov s KhOBL v ambulatorono-poliklinicheskikh usloviyakh / A.V. Budnevskiy, A.V.Pertsev, A.V. Chernov // Prikladnye informatsionnye aspekty meditsiny. 2015. T. 18, № 6. S. 52-56.